The mission of Mari Lowe Center for Comparative Oncology (MLCCO) is to develop a multidisciplinary program in oncology that exploits small animal spontaneous tumor models for use in understanding basic mechanisms of cancer and their treatment. This program is envisioned to also develop diagnostic and treatment modalities beneficial to both animal and human patients. Components of the program include basic, translational, and clinical research activities, and development of training programs in oncology. Members of MLCCO represent all four departments of the School of Veterinary Medicine. The Mari Lowe Center closely collaborates with the colleagues from the Abramson Cancer Center of the University of Pennsylvania and Comparative Oncology Research Group.