Laboratory for the Study of the Brain in Sleep

The following contains work since 2000, for a complete list of all work click here (complete list)

PAPERS:


1. Morrison, A.R., Sanford , L.D., and Ross, R.J., 2000. The amygdala: A critical modulator of sensory influence on sleep. Biological Signals and Receptors, 9:283-296.

2. Morrison, A.R. and Sanford , L.D., 2000. Critical brain characteristics to consider in developing dream and memory theories. Behavioral and Brain Sciences 23:977-97.

3. Sanford , L.D., Cheng, C.S., Silvestri, A.J., Tang, X., Mann, G.L., Ross, R.J., and Morrison, A.R., 2001. Sleep behavior in rats with pontine lesions producing REM without atonia. Sleep Res. Online, 4(1):1-5.

4. Sanford , L.D., Silvestri, A.J., Ross, R.J., and Morrison, A.R., 2001. Influence of fear conditioning on elicited ponto-geniculo-occipital waves and rapid eye movement sleep. Arch. Ital. Biol.,139:169-183.

5. Silvestri, A.J., Sanford , L.D., Pavlock, A., Ross, R.J. and Morrison, A.R., 2002. The central nucleus of the amygdala does not mediate the effects of modafinil. Brain Research, 941: 43-52.

6. Sanford , L.D., Tang, X., Ross, R.J., and Morrison, A.R. 2003. Influence of shock training and fear-conditioned cues on sleep architecture in mice: A strain comparison. Behavior Genetics, 33: 43-58.

7. Sanford, L.D., Tang, X., Xiao, J., Ross, R.J. and Morrison, A.R., 2003. GABAergic regulation of REM sleep in reticularis pontis oralis and caudalis in rats. J. Neurophysiol., 90: 938-945.

8. Amici, R., Sanford , L.D., Kearney , K., McInerney, B., Ross, R.J., Horner, R.L. and Morrison, A.R., 2004. A serotonergic (5-HT 2) receptor mechanism in the laterodorsal tegmental nucleus participates in regulating the pattern of rapid-eye-movement sleep occurrence in the rat. Brain Res., 996: 9-18.

9. Bush,W.W., Barr,C.S.; Stecker,M.M., Overall,K.L., Bernier,N. M., Darrin,E. W.; Morrison,A.R., 2004. Diagnosis of rapid eye movement sleep disorder with electroencephalography and treatment with tricyclic antidepressants in a dog. J. Amer. Anim. Hosp. Assoc., 40: 495-500.

10. Morrison, A.R., 2005. The power of behavioral analysis in understanding sleep mechanisms. In: P.L. Parmeggiani and R. Velluti, (Eds.), The Physiological Nature of Sleep, London, Imperial College Press, In press.

11. Pawlyk, A.C., Jha, S.K., Brennan, F.X., Morrison, A. R. and Ross, R.J. 2005. A rodent model of sleep disturbances in the anxiety disorders: the role of context following fear conditioning. Biol. Psychiatry, 57: 268-277.

12. Jha, S.K., Brennan, F.X., Pawlyk, A.C., Ross, R.J. and Morrison, A.R. 2005. REM sleep: a sensitive index of fear conditioning in rats. Eur. J. Neurosci., 21: 1077-1080.

13. Sanford , L.D., Yang, L., Tang, X., Ross, R.J., and Morrison, A.R.2005.Tetrodotoxin inactivation of pontine regions: effects on sleep-wake states. Brain Res., 1044: 42-50.

14 . Lu, J.W., Mann, G.L., Ross, R.J., Morrison, A.R. and Kubin, L. 2005. Differential effect of sleep-wake states on lingual and dorsal neck muscle activity in rats. Resp. Physiol. Neurobiol., 147: 191-203.

 

ARTICLES DEFENDING BIOMEDICAL RESEARCH:

1. Goodwin, F.K. and Morrison, A.R., 2000. Science and Self-Doubt. Why animal researchers must remember that human beings are special. Reason 32:22-29.

2. Morrison, A.R., 2001. Making choices in the laboratory. In: E.F. Paul and J. Paul (Eds.) Why Animal Experimentation Matters: The Use of Animals in Medical Research, New Studies in Social Policy Series: Piscataway : Transaction Press, p. 49-70.

3. Morrison, A.R., 2001. Personal reflections on the animal-rights phenomenon. Perspectives in Biology and Medicine, 44(winter 2001): 62-75. Reprinted in The Physiologist 44 (winter 2001):1, 7-13.

4. Morrison, A.R., 2001. A scientist's perspective on the ethics of using animals in behavioral research. In: M.E. Carroll, and J. B. Overmier (Eds.) Animal Research and Human Health: Advancing Human Welfare Through Behavioral Science, American Psychological Association, pp. 341-356.

5. Morrison, A.R., 2001. When sleep is not good for you. In: M. E. Carroll, and J. B. Overmier (Eds.), Animal Research and Human Health: Advancing Human Welfare through Behavioral Science, American Psychological Association, pp. 181-194.

6. Morrison, A.R., 2002. Developing an ethical view on the use of animals in biomedical research. The Fourth Walter C. Randall Lecture on Biomedical Ethics. The Physiologist, 45 (3): 135, 139-144.

7. Morrison, A.R., 2002. Misrepresenting medical history in the service of animal rights. Perspectives in Biology and Medicine, 45(autumn): 606-619.

8. Morrison, A.R. 2002. Making choices in the laboratory. Society, September/October: 16-23.

9. Morrison, A.R., 2003. Guest editorial: Animal-based research: our human obligation. The American Biology Teacher, 65: 645- 646.

10. Morrison, A.R., 2003. First, animals are not people. Long Beach Press-Telegram, Monday, August 6.

11. Morrison, A.R., 2003. Ethical principles guiding the use of animals in research. The American Biology Teacher, 65/2: 105- 108.

12. Morrison, A.R. 2003. The brain on night shift. Cerebrum, 5/3: 23-36.


LETTERS-TO-THE-EDITOR DEFENDING BIOMEDICAL RESEARCH:


1. Morrison, A.R., Why choose to use animals? Lab Animal 29/2:15, 2000.

2. Morrison, A.R., Medical history in question. The Am. Biol. Teacher 63/2:86, 2001.

3. Morrison, A.R. and Goodwin, F.K. Reply Letter: In defense of animal research. Reason 33, January, 2001, p. 6-9.

4. Morrison, A.R. Animal rites: To sleep, perchance to dream. New York Times, Editorials/Letters, January 31, 2001 , A20.

5. McInerney, J.D., Morrison, A.R., and Schrock, J.R. Reaction to “how we treat our relatives.” The Am. Bio. Teacher 66/4: 253-254, 2004.

BOOKS:

1. Fluharty, S.J. and Grill, H. J. (Eds.). Morrison, A.R. An analysis of the animal rights movement: its thinking, methods and successes. Progress in Psychobiology and Physiological Psychology, Academic Press, Vol. 18, 2001.

2. Orsini, P.G. and Morrison, A.R. Habel’s Guide to the Dissection of Domestic Ruminants, Published by the authors, 2004.

BOOK REVIEWS:

1. Morrison, A. 2001. Review: Awakenings in Sleep. The Paradox of Sleep: The Story of Dreaming. M. Jouvet translated by L. Garey. MIT Press, London (2000), 211 pp. In The Times Higher Education Supplement, Books 27, January 12, 2001 .


ABSTRACTS:

1. Sanford , L.D., R.J. Ross, and A.R. Morrison, 2000. Conditioned suppression of REM sleep in Sprague-Dawley (S-D) and Wistar-Kyoto (WKY) rats. Sleep 23, Suppl. 2:A145-146.

2. Silvestri, A.J., Pavlock, A., Sanford , L.D., Ross, R.J., and Morrison, A.R., 2000. The central nucleus of the amygdala (Ace) does not mediate the effects of modafinil. Soc. For Neurosci. Abstracts, 26: 1516.

3. Ross, R.J., Book, H.W., Sanford , L.D., Silver, S.M., Ford, N.M., Huff, R.M., and Morrison, A.R. 2001. REM activity increase in PTSD does not depend on a depressive diathesis and alcoholism. Sleep 24: A118.

4. Tang, X., Ross, R.J., Morrison, A.R., and Sanford, L.D. 2001. Telemetry for naturalistic sleep recording: results in inbred and hybrid mice. Sleep 24: A401.

5. Sanford ,L.D., Tang, X., Ross, R.J., and Morrison, A.R. 2001. Influence of anticipatory anxiety on sleep in behaviorally "anxious" and "non-anxious" mice. Sleep 24: A53.

6. Morrison, A.R., 2001. The animal biology of RBD: toward an understanding of human pathology. Actas de Fisiologia 7: 79.

7. Morrison, A.R., 2001. REM sleep without atonia: history of an animal model. Actas de Fisiologia 7: 55.

8. Sanford ,L.D., Tang, X., Ross, R.J., and Morrison, A.R. 2001. Gabaergic and adrenergic suppression of REM in N. subcoeruleus (SubC) and reticularis pontis caudalis (RPC). Actas de Fisiologia 7: 191.

9. Marchenko, V., Mann, G., Renik, V., Ross, R., and Morrison, A. 2001. Local gaba-ergic mechanisms are a major determinant of the level of activity in hypothalamic orexin-containing neurons. Actas de Fisiologia 7: 180.

10. Jha, S.K., Paull, D.S., Ross, R.J., and Morrison, A.R. 2002. NREM and REM sleep related neurons in the central nucleus of the amygdala and their modulation by dorsal raphe stimulation in rats. Sleep 25: A99.

11. Morrison, A.R. and Lathers, C.L. 2002. Central autonomic control of sleep and awaking processes. 5 th Head Out of Water Symposium, Houton , TX .

12. Sanford, L.D., Tang, X., Ross, R.J. and Morrison, A.R. 2002. Gabergic regulation of REM in n. reticularis pontis oralis and caudalis (RPO/RPC) in rats. Soc. Neurosci Abstr. 28: Online.

13. Kubin, L., Mann, G., Bloch, L., Ross, R., Morrison, A.R. 2002. Antagonism of hypothalamic perifornical GABA A receptors reduces sleep. Soc. Neurosci. Abstr. 28: 224.9.

14. Jha,S.K., Ross R.J. and Morrison, A.R. 2002. Effects of electrical stimulation of the dorsal raphe nucleus on sleep- related neurons in the central nucleus of amygdala. Soc. Neurosci. Abstr.28: 577.13.

15. Xiao,J., Tang, X., Ross, R.J., Morrison, A.R. and Sanford, L.D. 2003. Tetrodotoxin inactivation of pontine regions suppresses REM sleep. Sleep 26: A4.

16. Ross, R.J., Morrison, A.R., Sanford , L.D. and Jha, S.K. 2003. Suppression of REM sleep in rats recorded in a fearful context. Sleep 26: A 443.

17. Lu, W., Mann, G., Ross, R., Morrison, A.R. and Kubin, L. 2003. Antagonism of hypothalamic perifornical GABA Areceptors increases wakefulness during baseline sleep andfollowing sleep deprivation. Soc. Neurosci. Abstr. 29: 931.6.

18. Pawlyk, A.C., Jha, S.K., Brennan, F.X., Morrison, A.R., Ross, R.J. and Morrison, A.R. 2004. The role of context in differential sleep architecture changes following footshock. Sleep 27: A 407.

19. Lu, J.W., Mann, G.L., Ross, R.J., Morrison, A.R. and Kubin, L. 2004. REM sleep-suppressing effect of hypothalamic perifornical microperfusion with GABA A receptor antagonist, bicuculline, increases with the duration of sleep. Sleep 27 Suppl.: A14.

20. Jha, S.K., Pawlyk, A.C., Brennan, F.X., Ross, R.J., and Morrison, A.R. 2004.Conditioned fear cues suppress REM sleep in rats. Sleep 27 Suppl.: A28.

21. Lu, W., Mann, G.L., Ross, R., Morrison, A.R. and Kubin, L. 2004. Differential effect of slow-wave sleep (SWS) and REM sleep on dorsal neck and genioglossal muscle activity in rats. Soc. Neurosci. Abstr. 30: 663.11.

22. Lu, J.W., Mann, G.L., Volgin, D.V., Ross, R., Morrison, A.R. and Kubin, L. 2005.Perifornical hypothalamic microinjections of antisense oligodeoxynucleotides against â3 subunit of GABA A receptor reduce REM sleep.  Sleep 28 Suppl.: A28.

23. Pawlyk, A.C., Jha, S.K., Brennan,F.X., Morrison, A.R., and Ross, R.J. 2005. The differential rapid eye movement sleep response to cued and contextual fear conditioning is suppressed by a shared response to fearful conditioned stimuli. Sleep 28 Suppl.:. A346.

24. Tucker, A.M., Gehrman, P., Sanford , L.D., Morrison, A.R., Armitage, R. and Ross, R.J. 2005. Effect of anticipatory anxiety on sleep. Sleep 28 Suppl.: A314.