Walter Flato Goodman Center for Comparative Medical Genetics

Grant Support

Research Grants

Faculty Member

Faculty Member Role on Project and Grant Title

Source of Support Grant Number and Status

Aguirre, G

Translational Research for Retinal Degeneration Therapies

NIH EY-017549

Aguirre, G

Retinal remodeling in canine models of LCA/early onset RD

The Foundation Fighting Blindness

Aguirre, G

NDC for the Optical Control of Biological Function

NIH EY-01-8241

Artis, D

Functional biology of IL-25 following helminth infection

NIH AI-074878

Artis, D

Immuno-regulation of GI nematode infection

NIH AI-061570

Artis, D

Epithelial cell regulation of intestinal immune homeostasis

NIH AI-083480

Artis, D

Functional Biology of Intestinal Epithelial Cells in Food Allergy

NIH AI-087990

Artis, D

Tracking helminth-specific immune responses in vivo

Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Diseases

Atchison

Control of B Cell Development by YY1

NIH AI-079002

Atchison

Development control of enhancer function

NIH GM-082841

Avadhani, N

Role of Mitochondrial Respiratory Stress Signaling in Cancer Progression

NIH CA-022762

Avadhani, N

Role of Mitochondrial Targeted CYP2E1 and HO-1 in Alcohol Mediated Tissue Injury

NIH AA-017749

Avadhani, N

SUPPLEMENT- Role of Mitochondrial Targeted CYP2E1 and HO-1 in Alcohol Mediated Tissue Injury

NIH AA-017749

Avadhani, N

Mechanisms and Functions of Bimodally Targeted Cytochrome P450S to Mitochondria

NIH GM-034883

Bale, T

Actions of CRF on 5-HT pathways in mood regulation

NIH MH-073030

Bale, T

Early pregnancy stress programming of offspring emotionality

NIH MH-087597

Bale, T

Early gestation as a sensitive period to stress in sex-dependent neurodevelopment

NIH MH-091258

Bence

Neuronal protein tyrosine phosphatases in metabolism

NIH DK 082417

Bennett, J

Gene therapy for LCA due to CEP290 mutations

Donor: Project CEP290

Brinster, R

Regulation of Mouse Spermatogonial Stem Cell Self-Renewal

NIH HD052728

Brinster, R

Altering the Genes of Farm Animals

Kleberg Foundation

Cancro, M

Spinal Cord Injury and Immune Response to Viral Pathogen

Nielsen Foundation

Cancro, M

Mechanisms regulating plasma cell persistence in health and autoimmunity

Department of the Army W81WWXWH-10-1-0185

Cancro, M

Transitional B cell selection during peripheral B lymphopenia and reconstitution

NIH AI-073939

Cancro, M

Lymphocyte homeostasis and regulation during aging

NIH AG-030227

Cancro, M

Effects of induced B lymphopenia on homeostasis, selection, and immunity

Human Genome Sciences, Inc.

Felsburg, PJ

Gene Therapy for Canine X-linked SCID

NIH AI-043745

Fraser, N

Gene Transfer to and Expression in Neurons in Vivo

NIH NS-029390

Fraser, N

Mechanism of Latency of Herpes Simplex Virus

NIH NS-033768

Fraser, N

Gene Transfer to and Expression in Neurons in Vivo

NIH NS-029390

Hankenson

BMP6 Induction of Human Mesenchymal Stem Cell Osteoblast Differentiation

NIH DE-017471

Hankenson

Endosteal Adipose in Age-Associated Osteopenia

NIH AR-028922

Hankenson

Notch signaling in bone regeneration

Osteosynthesis and Trauma Care Foundation

Hankenson

Notch signaling in bone regeneration

Department of Defense (DOD) Peer Reviewed Orthopaedic Research Program (PRORP) Office of the Congressionally Directed Medical Research Programs (CDMRP).

Hankenson

Delivery of R-spondin2 using osteogenic biomaterials

Veterans Administration (VA) Merit Grant program

Hankenson

Notch Signaling in Bone Regeneration

Institute of Aging.  University of Pennsylvania

Haskins, ME

Gene Therapy of Mucopolysaccharidosis VII

NIH DK-054481

Haskins, ME

Gene Therapy in Alpha-Mannosodosis

NIH NS-061809

Haskins, ME

Animal Models of Human Genetic Diseases

NIH RR-02512

High, KA

Gene Therapy for Hemophilia using Muscle Expressed FVIIa

NIH HL-106300

High, KA

Pathway to Accelerate Clinical Development in Gene Transfer: cGMP Vector Core

NIH RR-030997

Hunter, C

Role of dendritic cells in resistance to T. gondii

NIH AI-071302

Hunter, C

Immunopathogenesis of Toxoplasmic Encephalitis

NIH AI-41158

Hunter, C

Regulation of the early immune response to Toxoplasma gondii

NIH AI-42334

Hunter, C

Understanding how IL-27 affects infection-induced responses by Treg cells.

Centocor

Hunter, C

Role of chemokines in the T cell response to ocular toxoplasmosis.

NIH EY-021314

Komaromy, AM

Achromatopsia - Disease Mechanisms and Cone Directed Gene Therapy

NIH EY-017549

Koretszky, G

Novel Substrates of the TCR Kinase

NIH GM-53256 (MERIT)

Koretszky, G

Project Leader (Project 1), Core Director (Core A) Temporal and Spatial Organization of Signaling complexes in T and B Cells

NIH CA-93615

Lopez, Christina

A novel virus-derived adjuvant

NIH AI-0803284

Lopez, Christina

Lung and bone marrow crosstalk during a respiratory viral infection

NIH AI-0803481

Lopez, Christina

Initial study of the dendritic cell response to defective viral particles

NIH AI-080917

Schifferli

The Psa fimbriae of Yersinia pestis, an adhesin with protective immunogenic properties

NIH AI-076695

Schifferli

Correlation of Salmonella colonization factors and antibiotic resistance by next generation sequencing.

University Research Foundation

Schifferli

Allelic diversity of Salmonella colonization and antibiotic resistance genes

Veterinary Center for Infectious Disease Research

Scott

IL-12 As an Immunopotentiator in Leishmaniasis

NIH AI-035914

Scott

Initiation of Immune Response in Chronic Leishmaniasis

NIH AI-076257

Scott

Myeloid Lineage Cells and Immunopathology in Leishmania

NIH AI-088650

Stedman, H

Systemic Molecular Therapy for Muscular Dystrophy

NIH NS-042874

Stedman, H

Shared Resource for Disease – Model Surgical Critical Care & Data Mgmt.

NIH

Stedman, H

Fecal DNA Biomarkers in Screening for Pancreatic Research

AACR

Vite

Collaborator; Gene Transfer & NMR studies in alpha-mannosidosis brain

NIH DK-63973

Vite

Intrathecal cyclodextrin therapy of feline Niemann-Pick type C disease

NIH NS-073661

Vite

Safety, Performance, and Efficacy of a Seizure Advisory System in Dogs with Epilepsy: A Pilot Study

NeuroVista Inc

Vite

Enzyme Replacement Therapy in Krabbe Disease in Dogs

Shire Pharmaceuticals Inc

Wilson, JM

Molecular Therapy for Cystic Fibrosis and Genetic Diseases

NIH DK-047757

Wilson, JM

DNA Virus as Vectors for Cardiovascular Diseases

NIH HL-059407

Wilson, JM

Gene Therapy Resource Program - Preclinical Vector Production

HHSN-268200748202C

Wilson, JM

Gene Therapy for Urea Cycle Disorders

NIH HD-057247

Wilson, JM

Regulated Transgene Expression in the Retina

NIH EY-020274

Wilson, JM

The Impact of Adenovirus Infections on HIV-1 Vaccine Performance

Gates Foundation 51061

Wilson, JM

Research Development Program– CF Pathophysiology and New Therapies

CFF-R881-CR07

Wilson, JM

AAV Vector Development

ReGenX  LLC

Winkelstein

Biomechanics of Neck Pain: Does Form Dictate Function?

NSF, BES (CAREER 0547451)

Winkelstein

NSF-GOALI Award

NSF –GOALI Award

Winkelstein

Nociceptive Mechanisms in Whiplash Injury

NIH AR-056288

Winkelstein

Electrophysiological Methods for Understanding Chronic Pain in Vivo

University Research Foundation Award- University Pennsylvania

Winkelstein

Building Interdisciplinary Research Teams

BIRT-AR-551895

Winkelstein

Salmon Thrombin as a Treatment to Attenuate Acute Pain & Promote Tissue Healing by Modulating Local Inflammation

DOD, CDMRP-HDA #OR090700

Winkelstein

Development of a Novel Translational Model of Vibration Injury to the Spine to Study Acute Injury in Vivo

DOD, CDMRP-TDA #OR090496

Winkelstein

Cervical Spine Human Surrogate Mechanical Investigations

US Army Research W911NF-07-D-0001

Wolfe

Gene transfer & NMR studies in alpha-mannosidosis brain

NIH DK-063973

Wolfe

Stem cell transplantation for neurogenetic disease

NIH NS-056243

Wolfe

Gene transfer to and expressions in neurons

NIH NS-029390

Wolfe

Pilot project: AAV vector gene transfer to manipulate the pontine micturition circuit

NIH DK-052620

Wolfe

Program in Comparative Animal Biology; Clinical and Translational Science Award

NIH RR-024134

Wolfe

AAV vector transduction in the brain in animal models of a lysosomal storage disease

NIH NS-038690

 

Center and Facility Grants

 

Training Grants

Program Director

Title of Training Grant

Funding Source Including Identifying Number

Atchison

Short-term Training: Students in Health Professional Schools

NIH RR-007065

Atchison

 

VMD-PhD training in infectious disease-related research

NIH AI-070077

Cancro MP

Immune System Development and Regulation

NIH AI-055428

Gaertner, DJ

Translational Research and Laboratory Animal Medicine Education for Veterinarians

NIH RR-032017

High K

Pediatric Hematology Research Training Program

NIH HL- 007150

Hunter CA

Parasitology: Modern Approaches

NIH AI-007532

Koretzky GA

Training Program Rheumatic Disease

NIH AR-007442