General & Systemic Pathology
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7a. Why does oliguria and anuria develop with ARF?
7b. Describe the pathogenesis that leads to this kind of renal injury.
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7a. Acute tubular necrosis results in shedding of tubular epithelial cells, which occludes the lumen of the tubule and form casts.
7b. This is the death by "poison" or death by "suffocation" story. There are numerous causes.