Center for Animal Health and Productivity

School of Veterinary Medicine New Bolton Center | 382 West Street Road Kennett Square, Pennsylvania 19348-1692

Spongiform Encephalopathies - Scrapie

Histopathological sections of brain from Scrapie affected sheep.

 

Image graciously found at UC Davis Vet School site.

Vacuoles are seen throughout the brain parenchyma. Proliferating reactive astrocytes have been counter-stained and appear brown.

 

Image graciously found at UC Davis Vet School site.

Higher Magnification. Single large empty vacuoles are seen in each of two neurons. These cytoplasmic vacuoles push the nucleus and other normal contents of cytoplasm to margins of the cell.